Certified Dialysis Nurse Practice Test

Swelling of the ankles is often associated with nephrosclerosis due to the impairment of kidney function that leads to fluid overload. Nephrosclerosis is a condition characterized by the hardening and thickening of the renal arterioles, which can affect the kidneys' ability to filter waste effectively. When kidney function declines, the body struggles to excrete excess fluid and sodium, leading to fluid retention and symptoms such as peripheral edema, which manifests as swelling in the ankles.

While nausea, shortness of breath, and increased thirst can occur as a result of various other health issues, they are not specific indicators of nephrosclerosis. Shortness of breath might occur due to fluid overload but is more commonly associated with heart issues or other pulmonary conditions. Nausea and thirst could result from multiple other factors, making them less directly indicative of nephrosclerosis compared to the clear relationship between reduced kidney function and swelling of the ankles.